Although recommendations can vary widely, most health organizations recommend a daily intake of at least 250–500 milligrams of EPA and DHA, the two essential forms of omega-3 fatty acids (24, 25, 26).
However, a higher amount is often recommended for people with certain health conditions, such as heart disease or high triglyceride levels (27).
For reference, a typical 1000 mg fish oil softgel generally contains around 250 mg of combined EPA and DHA, while a teaspoon (5 ml) of liquid fish oil is packaged in around 1,300 mg.
According to the European Food Safety Authority, omega-3 fatty acid supplements can be safely consumed in doses of up to 5,000 mg daily (24).
As a rule of thumb, if you experience negative symptoms, simply reduce your intake or consider getting your omega-3 fatty acid needs from food sources instead.
Summary Up to 5,000 mg of omega-3 fatty acids per day are considered safe. If you experience negative symptoms, reduce your intake or switch to food sources instead.